Antimicrobial Coatings for Medical Devices
Bacticent brand broad-spectrum antimicrobial coatings are a powerful weapon in the fight against healthcare associated infections.
According to a survey conducted by the Centers for Disease Control and Prevention (CDC), 722,000 healthcare-associated infections (HAIs) were reported in acute care hospitals in 2011.The CDC also reported that 75,000 hospital patients with HAIs died during their hospital stays.1
The patient impact can be significant, ranging from discomfort to death. Additionally infections can result in prolonged hospital stays, and serious subsequent consequences requiring future hospitalization and a shorter lifespan. The healthcare system also suffers by exposing healthcare workers to additional risk, consuming valuable resources and incurring additional expenses, which are often not reimbursed.
According to the American Medical Association, the total 2012 cost for the five most common HAIs was estimated to be $9.8 billion.2
Current best healthcare practices suggest the use of medical devices with an antimicrobial coating can go a long way toward eliminating these deadly infections.
Bacticent CHX features a highly effective antimicrobial coating precisely dosed and delivered right from the surface of your medical device. It is engineered to fight off the most common gram negative and gram positive bacteria associated with healthcare-associated infections. An example elution profile shows the delivery possible with Bacticent technology.
Catheters were cut into test segments and incubated in 10mM Phosphate buffer (pH 7.0) at 37° C and agitated at 50 RPM. The buffer was exchanged at regular intervals and the solutions were analyzed by HPLC for chlorhexidine concentration.
The competitor’s catheter exhibits greater initial release and faster depletion of chlorhexidine than the Bacticent CX coating with limited long-term (>30 days) effectiveness. The Bacticent CX coating release profile balances initial burst with a delayed release that extends effectiveness to 60 days.